Androgenreceptor相关论文
Discovery of novel antagonists targeting the DNA binding domain of androgen receptor by integrated d
Androgen receptor(AR),a ligand-activated transcription factor,is a master regulator in the development and progress of p......
目的:探讨三阴性乳腺癌（triple-negative breast cancer，TNBC）患者癌组织中雄激素受体（androgen receptor，AR）、Ki67的表达及与预后的关......
Bromodomain and extra-terminal proteins (BETs) are potential targets for the therapeutic treatment of prostate cancer (P......
Change of the cell cycle after flutamide treatment in prostate cancer cells and its molecular mechan
Aim: To explore the effect of androgen receptor (AR) on the expression of the cell cycle-related genes, such as CDKN1A a......
Aim: To investigate the localization and quantity of androgen receptor (AR) in the salivary glands of rats with further ......
Novel mutation in the ligand-binding domain of the androgen receptor gene (1790p) associated with co
Mutations in the X-linked androgen receptor (AR) gene cause androgen insensitivity syndrome (AIS), resulting in an impai......
Aim: To elucidate effects and mechanisms of emodin in prostate cancer cells. Methods: Viability of emodin-treated LNCaP ......
Aim: To investigate the role of CAG and GGN repeats as genetic background affecting androgen insensitivity syn- drome (A......
Androgen receptor expression in clinically localized prostate cancer: immunohistochemistry study and
Aim: To evaluate androgen receptor (AR) expression in clinically localized prostate cancer (Pca). Methods: Speci-mens we......
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Relationships among androgen receptor CAG repeat polymorphism, sex hormones and penile length in Han
This study aimed to investigate the correlations among androgen receptor (AR) CAG repeat polymorphism, sex hormones and ......
Androgen receptors expressed by prostatic stromal cells obtained from younger versus older males exh
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Androgen receptor gene CAG and GGN repeat lengths as predictors of recovery of spermatogenesis follo
Spermatogenesis is an androgen-regulated process that depends on the action of androgen receptor (AR). Sperm production ......
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The development and progression of metastatic castration-resistant prostate cancer is the major challenge in the treatme......
Androgen receptor deficiency in monocytes/macrophages does not alter adiposity or glucose homeostasi
Androgen deprivation in men leads to increased adiposity,but the mechanisms underlying androgen regulation of fat mass h......
Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human
The Y-located testis-specific protein Y-encoded (TSPY) and its X-homologue TSPX originated from the same ancestral gene,......
Despite great progress in the detection and treatment of prostate cancer,this disease remains an incredible health and e......
Prostate cancer (PCa) exhibits epidemiological and molecular heterogeneity.Despite extensive studies of its phenotypic a......
Androgen insensitivity syndrome (AIS),an X-linked recessive genetic disorder of sex development, is caused by mutations ......
Androgen receptor (AR),a hormonal transcription factor,plays important roles during prostate cancer progression and is a......
Dysfunctional sperm maturation is the primary reason for the poor sperm motility and morphology in infertile men.Spermat......
Estrogen receptor (α and β) but not androgen receptor expression is correlated with recurrence, prog
The objective of this study was to evaluate the expression of estrogen receptors (ER(α) and ER(β)) and androgen recept......
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Glucocorticoids have been used in the treatment of prostate cancer to slow disease progression, improve pain control and......
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We aimed to determine the mechanisms of the anabolic actions of androgens in skeletal muscle by investigating potential ......
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A missense mutation in the androgen receptor gene causing androgen insensitivity syndrome in a Chine
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Interrogation of onco-microRNA 125b reveals androgen receptor as a key upstream transcriptional fact
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Background:Ginseng,the root of Panax ginseng C.A.Meyer,has beneficialeffects on cardiovascular system.However,the molecu......
Histone H4 Lys 20 methyltransferase SET8 promotes androgen receptor-mediated transcription activatio
Histone methylation status in different lysine residues has an important role in transcription regulation.The effect of ......
The environmental endocrine disruptor p-nitrophenol interacts with FKBP51, a positive regulator of a
Objective: Although it was shown that p-nitrophenol is anti-androgenic in vivo,the molecular details of how p-nitropheno......
The androgen receptor (AR) plays a critical role in prostate cancer development and progression.The aim of this study is......
The ubiquitin-proteasome degradation pathway plays an essential role in multiple cellular processes, including cell cycl......
Androgen-independent LNCaP cell is a more aggressive phenotype subline of LNCaP cell and growth supp
Androgen deprivation therapy (ADT,surgical or chemical castration) is the mainstay treatment for metastatic PCa,but pati......
Sesquiterpenoids, isolated from Commiphora opobalsamum, induce cell cycle arrest and inhibit androge
Eight sesquiterpenoids were isolated from the resinous exudates of Commiphora opobalsamum.Their structures were establis......
